antiplatelet

Blood thinners are medicines that prevent blood clots from forming. They do not break up clots that you already have. But they can stop those clots from getting bigger. It's important to treat blood clots, because clots in your blood vessels and heart can cause heart attacks, strokes, and blockages.

You may need a blood thinner if you have:

• Certain heart or blood vessel diseases
• An abnormal heart rhythm called atrial fibrillation
• A heart valve replacement
• A risk of blood clots after surgery
• Congenital heart defects

There are different types of blood thinners:

• Anticoagulants, such as heparin or warfarin (also called Coumadin), slow down your body's process of making clots.
• Antiplatelets, such as aspirin and clopidogrel, prevent blood cells called platelets from clumping together to form a clot. Antiplatelets are mainly taken by people who have had a heart attack or stroke.

When you take a blood thinner, follow the directions carefully. Blood thinners may interact with certain foods, medicines, vitamins, and alcohol. Make sure that your health care provider knows all of the medicines and supplements you are using.

You may need regular blood tests to check how well your blood is clotting. It is important to make sure that you're taking enough medicine to prevent clots, but not so much that it causes bleeding.

Bleeding is the most common side effect of blood thinners. They can also cause an upset stomach, nausea, and diarrhea.

Other possible side effects can depend on which type of blood thinner that you are taking.

Call your provider if you have any sign of serious bleeding, such as:

• Menstrual bleeding that is much heavier than normal
• Red or brown urine
• Bowel movements that are red or black
• Bleeding from the gums or nose that does not stop quickly
• Vomit that is brown or bright red
• Coughing up something red
• Severe pain, such as a headache or stomachache
• Unusual bruising
• A cut that does not stop bleeding
• A serious fall or bump on the head
• Dizziness or weakness

A stroke happens when there is a loss of blood flow to part of the brain. Your brain cells cannot get the oxygen and nutrients they need from blood, and they start to die within a few minutes. This can cause lasting brain damage, long-term disability, or even death.

There are two main types of strokes, ischemic and hemorrhagic. Ischemic stroke is the more common type. An ischemic stroke happens when a blood clot blocks a blood vessel in the brain. Quick treatment can save a life and improve the chances of recovery.

Ischemic strokes are usually caused by one or more of the following:

• A blood clot. A clot can form in an artery that supplies the brain (thrombosis), or it can travel from another part of the body (embolism).
• Atherosclerosis. A disease in which plaque, a sticky substance made up of cholesterol, fat, and other substances, builds up inside your arteries.
• Irregular heart rhythms. Conditions like atrial fibrillation can cause clots to form in the heart, which may travel to the brain.
• Other heart and blood conditions. Such as heart valve diseases or sickle cell disease.

A transient ischemic attack (TIA) is caused by a brief blockage of blood flow to the brain. It usually lasts a few minutes. Having a TIA can mean you are at risk for having a more serious stroke.

Symptoms of stroke often happen suddenly. They include:

• Sudden numbness or weakness of the face, arm or leg (especially on one side of the body)
• Sudden confusion, trouble speaking or understanding speech
• Sudden trouble seeing in one or both eyes
• Sudden trouble walking, dizziness, loss of balance or coordination
• Sudden severe headache with no known cause

If you think someone is having a stroke, the F.A.S.T. test can help you remember what to look for. Think "FAST" and look for:

• Face drooping on one side when smiling.
• Arm weakness that occurs when the arms are raised, and one arm drifts downward.
• Speech is slurred or strange.
• Time to call 911.

To make a diagnosis, your health care provider may do a physical exam, ask about your symptoms and medical history, and use imaging tests. Other heart tests may be done to help find the cause of the stroke.

It is important to treat strokes as quickly as possible. The most common treatments include:

• Medicines such as blood thinners or thrombolytics (which break up and dissolve existing clots) may be used to prevent or treat ischemic stroke.
• Surgery or stenting may be used to open narrowed arteries or remove plaque build-up from the carotid arteries, which supply blood to the brain.

After treatment, rehabilitation can help you regain lost skills and independence. Your provider may also order other medicines to manage your blood pressure,cholesterol, or other health problems such as diabetes that may increase your risk for stroke.

The best way to prevent stroke is by making heart-healthy lifestyle changes to lower your risk. If lifestyle changes aren't enough, your provider may prescribe medicine to help manage your risk factors.

NIH: National Institute of Neurological Disorders and Stroke

Each year almost 800,000 Americans have a heart attack. A heart attack happens when blood flow to the heart suddenly becomes blocked. Without the blood coming in, the heart can't get oxygen. If not treated quickly, the heart muscle begins to die. But if you do get quick treatment, you may be able to prevent or limit damage to the heart muscle. That's why it's important to know the symptoms of a heart attack and call 911 if you or someone else is having them. You should call, even if you are not sure that it is a heart attack.

The most common symptoms in men and women are:

• Chest discomfort. It is often in center or left side of the chest. It usually lasts more than a few minutes. It may go away and come back. It can feel like pressure, squeezing, fullness, or pain. It also can feel like heartburn or indigestion.
• Shortness of breath. Sometimes this is your only symptom. You may get it before or during the chest discomfort. It can happen when you are resting or doing a little bit of physical activity.
• Discomfort in the upper body. You may feel pain or discomfort in one or both arms, the back, shoulders, neck, jaw, or upper part of the stomach.

You may also have other symptoms, such as nausea, vomiting, dizziness, and lightheadedness. You may break out in a cold sweat. Sometimes women will have different symptoms then men. For example, they are more likely to feel tired for no reason.

The most common cause of heart attacks is coronary artery disease (CAD). With CAD, there is a buildup of cholesterol and other material, called plaque, on their inner walls or the arteries. This is atherosclerosis. It can build up for years. Eventually an area of plaque can rupture (break open). A blood clot can form around the plaque and block the artery.

A less common cause of heart attack is a severe spasm (tightening) of a coronary artery. The spasm cuts off blood flow through the artery.

At the hospital, health care providers make a diagnosis based on your symptoms, blood tests, and different heart health tests. Treatments may include medicines and medical procedures such as coronary angioplasty. After a heart attack, cardiac rehabilitation and lifestyle changes can help you recover.

NIH: National Heart, Lung, and Blood Institute