blockers
Blood Pressure Medicines
What is high blood pressure?
High blood pressure, also called hypertension, is when blood puts too much pressure against the walls of your arteries. Almost half of American adults have high blood pressure, usually with no symptoms. But it can cause serious problems such as stroke, heart failure, heart attack, and kidney disease.
What lifestyle changes can help lower high blood pressure?
Healthy lifestyle changes can help reduce high blood pressure:
- Losing weight
- Being physically active
- Managing stress
- Reducing sodium in your diet
- Avoiding alcohol, tobacco, and illegal drugs
- Getting enough sleep
What if lifestyle changes alone cannot lower blood pressure?
Sometimes lifestyle changes alone cannot control or lower your high blood pressure. In that case, your health care provider may prescribe blood pressure medicines.
How do blood pressure medicines work?
The most commonly used blood pressure medicines work in different ways to lower blood pressure:
- Angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) keep your blood vessels from narrowing as much and allows blood to move through them with less pressure.
- Beta blockers help your heart beat slower and with less force. This means that your heart pumps less blood through your blood vessels. Beta blockers are typically used only as a backup option or if you also have certain other conditions.
- Calcium channel blockers prevent calcium from entering the muscle cells of your heart and blood vessels. This allows the blood vessels to relax.
- Diuretics remove extra water and sodium (salt) from your body. This lowers the amount of fluid in your blood. Diuretics are often used with other high blood pressure medicines, sometimes in one combined pill.
Often, two or more medicines work better than one. If these medicines do not lower your blood pressure enough, your provider may suggest that you take another type of blood pressure medicine.
While taking the medicines, it is still important to keep up with your healthy lifestyle changes. Doing both helps keep blood pressure lower than lifestyle changes or medicines alone.
NIH: National Heart, Lung, and Blood Institute
Raynaud Phenomenon
What is Raynaud phenomenon?
Raynaud phenomenon is a condition that affects your blood vessels (the tubes that your blood flows through). It causes your blood vessels to narrow, which decreases blood flow. This is called a Raynaud episode or "attack." The attacks usually affect your fingers and toes, causing them to become cold and numb. They may also change color, usually to white or blue. These attacks happen in response to cold temperatures or stress.
Raynaud phenomenon may also be called Raynaud disease or Raynaud syndrome.
What are the types of Raynaud phenomenon?
There are two types of Raynaud phenomenon:
- Primary Raynaud phenomenon is the more common type. Its cause is unknown.
- Secondary Raynaud phenomenon is usually caused by another disease or problem, such as lupus or scleroderma. Other causes may be exposure to cold or certain chemicals. The type can be more serious than the primary type.
What causes Raynaud phenomenon?
Researchers don't know exactly why some people develop Raynaud phenomenon. But they do understand how the attacks happen. When you are exposed to cold, your body tries to slow the loss of heat and maintain its temperature. To do this, the blood vessels in the top layer of your skin constrict (narrow). This moves blood from those vessels near the surface to vessels deeper in the body. But when you have Raynaud phenomenon, the blood vessels in your hands and feet react to cold or stress by narrowing quickly. They also stay narrowed for a long time.
Who is more likely to develop Raynaud phenomenon?
Anyone can develop Raynaud phenomenon, but some people are more likely to develop it:
- Primary Raynaud phenomenon has been linked to:
- Your sex. Women get it more often than men.
- Your age. It usually develops in people younger than age 30. It often starts in the teenage years.
- A family history of Raynaud phenomenon. You are more likely to develop Raynaud phenomenon if you have a family member who has it.
- Secondary Raynaud phenomenon has been linked to:
- Certain diseases. These include lupus, scleroderma, rheumatoid arthritis (RA), carpal tunnel syndrome, and connective tissue disorders.
- Certain medicines. Medicines that treat high blood pressure, migraines, and attention deficit hyperactivity disorder (ADHD) may cause similar symptoms to Raynaud phenomenon or make your symptoms worse.
- Work-related exposures, such as repeated use of vibrating machinery (such as a jackhammer), or exposure to cold or certain chemicals.
What are the symptoms of Raynaud phenomenon?
Raynaud attacks most often happen when you get cold, for example when you grab something cold from the freezer or go into an air-conditioned building on a warm day. Attacks usually affect your fingers and toes. But sometimes they can affect other parts of your body, such as your ears, nose, lips, or nipples.
An attack causes the skin to become cold and numb. Your skin may also turn white or blue due to a lack of oxygen. As the blood flow returns, your skin may tingle, throb, or turn red. An attack may last a few minutes or a few hours. If you have darker skin, you may not be able to easily see the skin color changes.
For many people, especially those with the primary type, the symptoms are mild. People with the secondary type often have more severe symptoms. They may develop skin ulcers (open sores caused by poor blood flow) or skin infections.
How is Raynaud phenomenon diagnosed?
There is no specific test to diagnose Raynaud phenomenon. To find out if you have it, your health care provider:
- Will take your medical history and ask about your symptoms.
- Will do a physical exam.
- May order blood and other lab tests to check for other conditions which could be causing your symptoms and/or to help decide which type of Raynaud phenomenon you have.
What are the treatments for Raynaud phenomenon?
Most people with Raynaud phenomenon can keep their symptoms under control by avoiding getting cold. But if this is not enough, medicines and, in some cases, surgical procedures can help.
Secondary Raynaud phenomenon is more likely to be serious and to need more treatments. It's also important to treat the condition or problem that is causing your Raynaud phenomenon.
You may need to see a specialist such as a rheumatologist, a doctor who treats diseases of the joints, muscles, and bones.
Can Raynaud phenomenon be prevented?
Raynaud phenomenon cannot be prevented, but you can help prevent attacks and manage your symptoms by:
- Placing your hands or feet in a warm place when you have an attack. This could mean putting them under warm (not hot) water or under a heating pad.
- Keeping your body, especially your hands and feet, warm in cold weather.
- Avoiding triggers, such as certain medicines and stress.
- Quitting smoking (or not starting smoking).
- Managing stress.
NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases
Angina
Angina is chest pain or discomfort you feel when there is not enough blood flow to your heart muscle. Your heart muscle needs the oxygen that the blood carries. Angina may feel like pressure or a squeezing pain in your chest. It may feel like indigestion. You may also feel pain in your shoulders, arms, neck, jaw, or back.
Angina is a symptom of coronary artery disease (CAD), the most common heart disease. CAD happens when a sticky substance called plaque builds up in the arteries that supply blood to the heart, reducing blood flow.
There are three types of angina:
- Stable angina is the most common type. It happens when the heart is working harder than usual. Stable angina has a regular pattern. Rest and medicines usually help.
- Unstable angina is the most dangerous. It does not follow a pattern and can happen without physical exertion. It does not go away with rest or medicine. It is a sign that you could have a heart attack soon.
- Variant angina is rare. It happens when you are resting. Medicines can help.
Not all chest pain or discomfort is angina. If you have chest pain, you should see your health care provider.
NIH: National Heart, Lung, and Blood Institute
Body Weight
What is body weight?
Body weight is the total mass of your body. Keeping track of your weight is one way to check for changes in your health, but it can't tell you the whole story. That's because your weight includes muscle, bone, fat, and water. Also, everyday factors can play a role in your weight, such as your:
- Diet
- Activity level
- Stress level
- Sleep habits
- Family history and genetics
- Age
What factors help determine a healthy body weight?
A healthy weight is more than just a number on the scale. It's about feeling good, having energy, and lowering your risk of disease. Your health care provider can help you determine a healthy body weight based on several factors. These include your:
- Body Mass Index (BMI). BMI is a measure of how much you weigh compared to how tall you are. The higher your BMI, the higher your risk for certain diseases. BMI does not distinguish between fat, muscle, and bone mass. It also may overestimate body fat in athletes or those with a muscular build, or underestimate body fat in older persons or others who have lost muscle.
- Waist circumference. If most of your body fat is around your abdomen (belly) rather than your hips, you may be at a higher risk for heart disease and type 2 diabetes.
- Health history. Your health care provider will likely consider your risk factors for diseases and health conditions, such as having high cholesterol, in determining your healthy body weight.
What are body weight ranges?
Having a healthy body weight may lower your chance of developing certain health problems. Carrying too much or too little weight can affect your health. Ranges of body weight include:
- Underweight. Your weight is lower than it should be for your health.
- Normal. Your weight is within a healthy range.
- Overweight. Your weight is greater than it should be for your health.
- Obese. Your body fat is greater than it should be for your health.
Body weight needs can be different at different ages. For children, weight and growth are tracked over time based on their age. For older adults, keeping muscle and strength is key, and sudden weight loss should always be checked by your provider.
What if I have a sudden gain or loss of weight?
Talk to your provider if you're losing or gaining weight without trying. A sudden, unexpected change in weight can be a sign of a medical problem.
Causes for sudden weight loss can include:
- Thyroid problems
- Cancer
- Infectious diseases
- Digestive diseases
- Certain medicines
Causes for sudden weight gain can include:
- Certain medicines
- Thyroid problems
- Heart failure
- Kidney disease
- Liver disease
How can I maintain a healthy body weight?
Maintaining a healthy body weight can improve energy, sleep, and overall wellbeing. Talk to your provider about what a healthy weight would be for you. If they recommend that you gain or lose weight, they might refer you to a dietician for support. A dietician is a professional who has special training to help you learn the best way to eat.
- Good nutrition and exercise can help in losing weight. Even a small change in weight can lower your risk of developing certain diseases.
- Eating extra calories within a well-balanced diet and treating any underlying medical problems can help you gain weight.
Focus on your health, not just the number on the scale. With daily healthy habits and self-compassion, you can support lasting improvements in your overall wellbeing.
NIH: National Heart, Lung, and Blood Institute
HDL: The "Good" Cholesterol
What is cholesterol?
Cholesterol is a waxy, fat-like substance that's found in all the cells in your body. Your liver makes cholesterol, and it is also in some foods, such as meat and dairy products. Your body needs some cholesterol to work properly. But having too much cholesterol in your blood raises your risk of coronary artery disease.
What are HDL and LDL?
HDL and LDL are two types of lipoproteins.They are a combination of fat (lipid) and protein. The lipids need to be attached to the proteins so they can move through the blood. HDL and LDL have different purposes:
- HDL stands for high-density lipoproteins. It is sometimes called the "good" cholesterol because it carries cholesterol from other parts of your body back to your liver. Your liver then removes the cholesterol from your body.
- LDL stands for low-density lipoproteins. It is sometimes called the "bad" cholesterol because a high LDL level leads to a buildup of cholesterol in your arteries.
How do I know what my HDL level is?
A blood test can measure your cholesterol levels, including HDL. When and how often you should get this test depends on your age, risk factors, and family history. The general recommendations are:
For people who are age 19 or younger::
- The first test should be between ages 9 to 11
- Children should have the test again every 5 years
- Some children may have this test starting at age 2 if there is a family history of high blood cholesterol, heart attack, or stroke
For people who are age 20 or older::
- Younger adults should have the test every 5 years
- Men ages 45 to 65 and women ages 55 to 65 should have it every 1 to 2 years
What should my HDL level be?
With HDL cholesterol, higher numbers are better, because a high HDL level can lower your risk for coronary artery disease and stroke. How high your HDL should be depends on your age and sex:
GroupHealthy HDL LevelAge 19 or youngerMore than 45mg/dlMen age 20 or olderMore than 40mg/dlWomen age 20 or olderMore than 50mg/dlHow can I raise my HDL level?
If your HDL level is too low, lifestyle changes may help. These changes may also help prevent other diseases, and make you feel better overall:
- Eat a healthy diet. To raise your HDL level, you need to eat good fats instead of bad fats. This means limiting saturated fats, which include full-fat milk and cheese, high-fat meats like sausage and bacon, and foods made with butter, lard, and shortening. You should also avoid trans fats, which may be in some margarines, fried foods, and processed foods like baked goods. Instead, eat unsaturated fats, which are found in avocado, vegetable oils like olive oil, and nuts. Limit carbohydrates, especially sugar. Also try to eat more foods naturally high in fiber, such as oatmeal and beans.
- Stay at a healthy weight. You can boost your HDL level by losing weight, especially if you have lots of fat around your waist.
- Exercise. Getting regular exercise can raise your HDL level, as well as lower your LDL. You should try to do 30 minutes of moderate to vigorous aerobic exercise on most, if not all, days.
- Avoid cigarettes.Smoking and exposure to secondhand smoke can lower your HDL level. If you are a smoker, ask your health care provider for help in finding the best way for you to quit. You should also try to avoid secondhand smoke.
- Limit alcohol. Moderate alcohol may lower your HDL level, although more studies are needed to confirm that. What we do know is that too much alcohol can make you gain weight, and that lowers your HDL level.
Some cholesterol medicines, including certain statins, can raise your HDL level, in addition to lowering your LDL level. Health care providers don't usually prescribe medicines only to raise HDL. But if you have a low HDL and high LDL level, you might need medicine.
What else can affect my HDL level?
Taking certain medicines can lower HDL levels in some people. They include:
- Beta blockers, a type of blood pressure medicine
- Anabolic steroids, including testosterone, a male hormone
- Progestins, which are female hormones that are in some birth control pills and hormone replacement therapy
- Benzodiazepines, sedatives that are often used for anxiety and insomnia
If you are taking one of these and you have a very low HDL level, ask your provider if you should continue to take them.
Diabetes can also lower your HDL level, so that gives you another reason to manage your diabetes.
Heart Attack
Each year almost 800,000 Americans have a heart attack. A heart attack happens when blood flow to the heart suddenly becomes blocked. Without the blood coming in, the heart can't get oxygen. If not treated quickly, the heart muscle begins to die. But if you do get quick treatment, you may be able to prevent or limit damage to the heart muscle. That's why it's important to know the symptoms of a heart attack and call 911 if you or someone else is having them. You should call, even if you are not sure that it is a heart attack.
The most common symptoms in men and women are:
- Chest discomfort. It is often in center or left side of the chest. It usually lasts more than a few minutes. It may go away and come back. It can feel like pressure, squeezing, fullness, or pain. It also can feel like heartburn or indigestion.
- Shortness of breath. Sometimes this is your only symptom. You may get it before or during the chest discomfort. It can happen when you are resting or doing a little bit of physical activity.
- Discomfort in the upper body. You may feel pain or discomfort in one or both arms, the back, shoulders, neck, jaw, or upper part of the stomach.
You may also have other symptoms, such as nausea, vomiting, dizziness, and lightheadedness. You may break out in a cold sweat. Sometimes women will have different symptoms then men. For example, they are more likely to feel tired for no reason.
The most common cause of heart attacks is coronary artery disease (CAD). With CAD, there is a buildup of cholesterol and other material, called plaque, on their inner walls or the arteries. This is atherosclerosis. It can build up for years. Eventually an area of plaque can rupture (break open). A blood clot can form around the plaque and block the artery.
A less common cause of heart attack is a severe spasm (tightening) of a coronary artery. The spasm cuts off blood flow through the artery.
At the hospital, health care providers make a diagnosis based on your symptoms, blood tests, and different heart health tests. Treatments may include medicines and medical procedures such as coronary angioplasty. After a heart attack, cardiac rehabilitation and lifestyle changes can help you recover.
NIH: National Heart, Lung, and Blood Institute
Hyperthyroidism
What is hyperthyroidism?
Hyperthyroidism, or overactive thyroid, happens when your thyroid gland makes more thyroid hormones than your body needs.
Your thyroid is a small, butterfly-shaped gland in the front of your neck. It makes hormones that control the way the body uses energy. These hormones affect nearly every organ in your body and control many of your body's most important functions. For example, they affect your breathing, heart rate, weight, digestion, and moods. If not treated, hyperthyroidism can cause serious problems with your heart, bones, muscles, menstrual cycle, and fertility. But there are treatments that can help.
What causes hyperthyroidism?
Hyperthyroidism has several causes. They include:
- Graves' disease, an autoimmune disorder in which your immune system attacks your thyroid and causes it to make too much hormone. This is the most common cause.
- Thyroid nodules, which are growths on your thyroid. They are usually benign (not cancer). But they may become overactive and make too much thyroid hormone. Thyroid nodules are more common in older adults.
- Thyroiditis, inflammation of the thyroid. It causes stored thyroid hormone to leak out of your thyroid gland.
- Too much iodine. Iodine is found in some medicines, cough syrups, seaweed and seaweed-based supplements. Taking too much of them can cause your thyroid to make too much thyroid hormone.
- Too much thyroid medicine. This can happen if people who take thyroid hormone medicine for hypothyroidism (underactive thyroid) take too much of it.
Who is at risk for hyperthyroidism?
You are at higher risk for hyperthyroidism if you:
- Are a woman
- Are older than age 60
- Have been pregnant or had a baby within the past 6 months
- Have had thyroid surgery or a thyroid problem, such as goiter
- Have a family history of thyroid disease
- Have pernicious anemia, in which the body cannot make enough healthy red blood cells because it does not have enough vitamin B12
- Have type 1 diabetes or primary adrenal insufficiency, a hormonal disorder
- Get too much iodine, from eating large amounts of foods containing iodine or using iodine-containing medicines or supplements
What are the symptoms of hyperthyroidism?
The symptoms of hyperthyroidism can vary from person to person and may include:
- Nervousness or irritability
- Fatigue
- Muscle weakness
- Trouble tolerating heat
- Trouble sleeping
- Tremor, usually in your hands
- Rapid and irregular heartbeat
- Frequent bowel movements or diarrhea
- Weight loss
- Mood swings
- Goiter, an enlarged thyroid that may cause your neck to look swollen. Sometimes it can cause trouble with breathing or swallowing.
Adults over age 60 may have different symptoms than younger adults. For example, they may lose their appetite or withdraw from other people. Sometimes this can be mistaken for depression or dementia.
What other problems can hyperthyroidism cause?
If hyperthyroidism isn't treated, it can cause some serious health problems, including:
- An irregular heartbeat that can lead to blood clots, stroke, heart failure, and other heart problems
- An eye disease called Graves' ophthalmopathy. It can cause double vision, light sensitivity, and eye pain. In rare cases, it can lead to vision loss.
- Thinning bones and osteoporosis
- Fertility problems in women
- Complications in pregnancy, such as premature birth, low birth weight, high blood pressure in pregnancy, and miscarriage
How is hyperthyroidism diagnosed?
Your health care provider may use many tools to make a diagnosis:
- A medical history, including asking about symptoms
- A physical exam
- Thyroid tests, such as
- TSH, T3, T4, and thyroid antibody blood tests
- Imaging tests, such as a thyroid scan, ultrasound, or radioactive iodine uptake test. A radioactive iodine uptake test measures how much radioactive iodine your thyroid takes up from your blood after you swallow a small amount of it.
What are the treatments for hyperthyroidism?
The treatments for hyperthyroidism include medicines, radioiodine therapy, and thyroid surgery:
- Medicines for hyperthyroidism include
- Antithyroid medicines, which cause your thyroid to make less thyroid hormone. You probably need to take the medicines for 1 to 2 years. In some cases, you might need to take the medicines for several years. This is the simplest treatment, but it is often not a permanent cure.
- Beta blocker medicines, which can reduce symptoms such as tremors, rapid heartbeat, and nervousness. They work quickly and can help you feel better until other treatments take effect.
- Radioiodine therapy is a common and effective treatment for hyperthyroidism. It involves taking radioactive iodine by mouth as a capsule or liquid. This slowly destroys the cells of the thyroid gland that produce thyroid hormone. It does not affect other body tissues. Almost everyone who has radioactive iodine treatment later develops hypothyroidism. This is because the thyroid hormone-producing cells have been destroyed. But hypothyroidism is easier to treat and causes fewer long-term health problems than hyperthyroidism.
- Surgery to remove part or most of the thyroid gland is done in rare cases. It might be an option for people with large goiters or pregnant women who cannot take antithyroid medicines. If you have all of your thyroid removed, you will need to take thyroid medicines for the rest of your life. Some people who have part of their thyroid removed also need to take medicines.
If you have hyperthyroidism, it's important not to get too much iodine. Talk to your health care provider about which foods, supplements, and medicines you need to avoid.
NIH: National Institute of Diabetes and Digestive and Kidney Diseases