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Uterine cancer is a cancer that forms in tissues of the uterus, which is sometimes called the womb. The uterus is the place where a fetus grows during pregnancy.

There are two types of uterine cancer:

• Endometrial cancer is the most common type. This type of cancer begins in the cells lining the uterus, known as the endometrium.
• Uterine sarcoma is a rare, more aggressive cancer that is harder to treat. This type of cancer begins in muscle or other tissues in the uterus.

Uterine cancer usually happens after menopause. The cause is unknown. However, some factors and conditions that change the balance of hormones in your body may increase your risk. These can include obesity or metabolic syndrome (a group of risk factors for certain health problems).

Other factors and conditions that may increase your risk for:

Endometrial cancer

• Taking estrogen-only hormone replacement therapy (HRT) after menopause.
• Having type 2 diabetes.
• Starting menstruation at an early age or menopause at a later age.
• Having never been pregnant.
• Taking tamoxifen, a medicine used to prevent or treat breast cancer.
• Having polycystic ovary syndrome.
• Having a mother, sister, or daughter who has had endometrial cancer.
• Having certain genetic conditions, such as Lynch syndrome.
• Having endometrial hyperplasia (thickening of the uterine lining).

Uterine sarcoma

• Having had past treatment with radiation therapy to the pelvis.
• Taking tamoxifen, a medicine used to prevent or treat breast cancer.

The most common symptom of both endometrial cancer and uterine sarcoma is abnormal vaginal bleeding. Both types of uterine cancer may also cause pelvic pain or pressure, unusual vaginal discharge, or an enlarged uterus or pelvic mass.

Less common symptoms may include urinating (peeing) often, having trouble urinating, or pain during sexual intercourse.

If you have symptoms of uterine cancer, your health care provider may:

• Ask about your medical history and family health history.
• Do a pelvic exam.
• Order imaging tests.
• Suggest a biopsy or a minor procedure called dilation and curettage (D & C) to check the lining of your uterus.

Treatment may depend on your health, how much cancer you have, and whether it has spread. The most common treatment is having a hysterectomy, which is surgery to remove the uterus. Sometimes the surgery also removes the ovaries and fallopian tubes.

You may have more than one type of treatment. Other treatments may include:

• Hormone therapy
• Radiation therapy
• Chemotherapy

There is no sure way to prevent uterine cancer. But you can do things that may help lower your risk such as aiming for a healthy weight, getting regular physical activity, and talking to your provider about the benefits and risks of hormone therapy.

NIH: National Cancer Institute

An induced abortion is a procedure to end a pregnancy. It can be done two different ways:

• Medication abortion (also called medical abortion)
• Procedural abortion

An induced abortion is different from a spontaneous abortion. That is the loss of a pregnancy before the 20th week of pregnancy. It is more commonly known as a miscarriage.

If you are thinking of having an induced abortion, talk with your health care provider. Your provider can explain how the procedures are done, as well as the risks and benefits of each.

The uterus, or womb, is the place where a fetus grows during pregnancy. In an ectopic pregnancy, the fertilized egg grows in the wrong place outside the uterus. It usually occurs in the fallopian tubes. These tubes carry eggs from the ovaries to the uterus. Sometimes, an ectopic pregnancy can occur in the ovaries, abdominal cavity, or the lower part of the uterus (cervix).

Ectopic pregnancies can't end in a healthy pregnancy because the egg cannot grow. If the pregnancy continues, the fallopian tube can burst. This can cause internal bleeding, which can be a life-threatening emergency that needs immediate surgery.

An ectopic pregnancy often happens because there is a problem with your fallopian tubes. But sometimes it's not clear why an ectopic pregnancy happens.

Factors that may increase your risk for an ectopic pregnancy can include:

• Previous ectopic pregnancy
• Prior pelvic, abdominal, or fallopian tube surgery
• Certain sexually transmitted infections (STIs)
• Pelvic inflammatory disease
• Endometriosis
• Becoming pregnant while using an intrauterine device (IUD) for birth control
• Becoming pregnant after a tubal ligation

Other factors that may increase your risk can include:

• Smoking
• Being older than age 35
• Infertility treatments

You may not notice any symptoms at first. Or you may have some of the usual signs of pregnancy such as a missed period, breast tenderness, or nausea.

Early signs of an ectopic pregnancy may be light vaginal bleeding and pelvic pain. Ectopic pregnancy can be a medical emergency. Get medical care right away if you have these signs:

• Abdominal (belly) pain
• Shoulder pain
• Vaginal bleeding
• Feeling dizzy or faint

An ectopic pregnancy can't be diagnosed without blood tests and an ultrasound. Your health care provider will do a pregnancy test to confirm that you're pregnant. They may do a pelvic exam to check for areas of pain, tenderness, or a mass.

An ectopic pregnancy needs treatment to stop any damage to your organs. Your provider will use medicine or surgery to take out the ectopic tissue.

Losing a pregnancy can be devastating. An ectopic pregnancy is like a miscarriage, but it must be treated to prevent problems. People cope with grief in different ways. It may be helpful to discuss your feelings with your provider or a counselor. Many women who have had ectopic pregnancies go on to have healthy pregnancies later.

Dept. of Health and Human Services Office on Women's Health

Eosinophilic esophagitis (EoE) is a chronic disease of the esophagus. Your esophagus is the muscular tube that carries food and liquids from your mouth to the stomach. If you have EoE, white blood cells called eosinophils build up in your esophagus. This causes damage and inflammation, which can cause pain, trouble swallowing, and food getting stuck in your throat.

EoE is rare. But because it is a newly recognized disease, it is being diagnosed more often. Some people who think that they have reflux (GERD) may actually have EoE.

Researchers are not certain about the exact cause of EoE. They think that it is an immune system/allergic reaction to foods or to substances in your environment, such as dust mites, animal dander, pollen, and molds. Certain genes may also play a role in EoE.

EoE can affect anyone, but it is more common in people who:

• Are male
• Have other allergic diseases, such as hay fever, eczema, asthma and food allergies
• Have family members with EoE

The most common symptoms of EoE can depend on your age.

In infants and toddlers::

• Feeding problems
• Vomiting
• Poor weight gain and growth
• Reflux that does not get better with medicines

In older children::

• Vomiting
• Abdominal pain
• Trouble swallowing, especially with solid foods
• Reflux that does not get better with medicines
• Poor appetite

In adults::

• Trouble swallowing, especially with solid foods
• Food getting stuck in the esophagus
• Reflux that does not get better with medicines
• Heartburn
• Chest pain

To find out if you have EoE, your doctor will likely:

• Ask about your symptoms and medical history. Since other conditions can have the same symptoms of EoE, it is important for your doctor to take a thorough history.
• Do an upper gastrointestinal (GI) endoscopy. An endoscope is a long, flexible tube with a light and camera at the end of it. Your doctor will run the endoscope down your esophagus and look at it. Some signs that you might have EoE include white spots, rings, narrowing, and inflammation in the esophagus. However, not everyone with EoE has those signs, and sometimes they can be signs of a different esophagus disorder.
• Do a biopsy. During the endoscopy, the doctor will take small tissue samples from your esophagus. The samples will be checked for a high number of eosinophils. This is the only way to make a diagnosis of EoE.
• Do other tests as needed. You may have blood tests to check for other conditions. If you do have EoE, you may have blood or other types of tests to check for specific allergies.

There is no cure for EoE. Treatments can manage your symptoms and prevent further damage. The two main types of treatments are medicines and diet.

Medicines used to treat EoE are:

• Steroids, which can help control inflammation. These are usually topical steroids, which you swallow either from an inhaler or as a liquid. Sometimes doctors prescribe oral steroids (pills) to treat people who have serious swallowing problems or weight loss.
• Acid suppressors such as proton pump inhibitors (PPIs), which may help with reflux symptoms and decrease inflammation.
• Monoclonal antibodies, which can reduce inflammation and may help with swallowing. They can be used in adults and children over age 12.

Dietary changes for EoE include:

• Elimination diet. If you are on an elimination diet, you stop eating and drinking certain foods and beverages for several weeks. If you are feeling better, you add the foods back to your diet one at a time. You have repeat endoscopies to see whether or not you are tolerating those foods. There are different types of elimination diets:
• With one type, you first have an allergy test. Then you stop eating and drinking the foods you are allergic to.
• For another type, you eliminate foods and drinks that commonly cause allergies, such as dairy products, egg, wheat, soy, peanuts, tree nuts and fish/shellfish.
• Elemental diet. With this diet, you stop eating and drinking all proteins. Instead, you drink an amino acid formula. Some people who do not like the taste of the formula use a feeding tube instead. If your symptoms and inflammation go away completely, you may be able to try adding foods back one at a time, to see whether you can tolerate them.

Which treatment your doctor suggests depends on different factors, including your age. Some people may use more than one kind of treatment. Researchers are still trying to understand EoE and how best to treat it.

If your treatment is not working well enough and you have narrowing of the esophagus, you may need dilation. This is a procedure to stretch the esophagus. This makes it easier for you to swallow.

A miscarriage is an unexpected loss of pregnancy before the 20th week. Most miscarriages happen very early in the pregnancy, often before a woman even knows she is pregnant.

A miscarriage can happen in any pregnancy. Most miscarriages occur because the fetus doesn't develop properly. This is often linked to a genetic problem with the fetus, such as an extra or missing chromosome.

In many cases, the cause of a miscarriage is unknown. Some possible factors that may increase the chance of a miscarriage can include:

• Problems with the uterus or cervix
• Chronic diseases, including polycystic ovary syndrome
• Genetic problems with the fetus
• Pregnancy after 35 years of age
• Smoking, drug or alcohol use
• Certain chronic (long-term) health conditions, such as uncontrolled diabetes
• Severe malnutrition

The signs of a miscarriage may be different for everyone and can vary based on how far along you are in your pregnancy.

Signs of a miscarriage can include:

• Vaginal spotting or bleeding with or without pain. Some women may have some spotting in early pregnancy and don't miscarry. To be sure, contact your provider right away if you have any bleeding.
• Dark-colored vaginal discharge.
• A gush of fluid or tissue from your vagina.
• Cramping or pain in your abdomen (belly) or lower back.

Sometimes, it's hard to know what's normal during pregnancy. If something seems unusual or is worrying you, talk to your provider.

To check if you have had a miscarriage, your provider may do the following:

• A pelvic exam to check your cervix.
• Blood tests to check things such as the amount of blood loss and confirm pregnancy.
• An ultrasound to check the fetus.

Treatment after a miscarriage often depends on when it occurs during the pregnancy. If you miscarry early in your pregnancy, you may not need any treatment. If you are 12 or more weeks pregnant, you may need a shot to prevent problems with the Rh factor in future pregnancies.

In some cases, tissue is left in the uterus. If you don't have any signs of infection, your provider may recommend waiting for the tissue to pass naturally. If you need treatment to remove the tissue, it can include:

• Medicines
• A procedure called dilatation and curettage (D&C) or vacuum aspiration

No matter when it occurs, losing a pregnancy can be difficult. Counseling may help you cope with your grief. Later, if you decide to try to get pregnant again, talk with your provider to understand any risks. Many women who have a miscarriage go on to have healthy pregnancies later.

Miscarriage can affect anyone and often can't be prevented. Focus on taking good care of yourself and start prenatal care visits early in your pregnancy.

NIH: National Institute of Child Health and Human Development

Traumatic brain injury (TBI) is a sudden injury that causes damage to the brain. It may happen when there is a blow, bump, or jolt to the head. This is a closed head injury. A TBI can also happen when an object penetrates the skull. This is a penetrating injury.

Symptoms of a TBI can be mild, moderate, or severe. Concussions are a type of mild TBI. The effects of a concussion can sometimes be serious, but most people completely recover in time. More severe TBI can lead to serious physical and psychological symptoms, coma, and even death.

The main causes of TBI depend on the type of head injury:

• Some of the common causes of a closed head injury include
  • Falls. This is the most common cause in adults age 65 and older.
  • Motor vehicle crashes. This is the most common cause in young adults.
  • Sports injuries
  • Being struck by an object
  • Child abuse. This is the most common cause in children under age 4.
  • Blast injuries due to explosions
• Some of the common causes of a penetrating injury include
  • Being hit by a bullet or shrapnel
  • Being hit by a weapon such as a hammer, knife, or baseball bat
  • A head injury that causes a bone fragment to penetrate the skull

Some accidents such as explosions, natural disasters, or other extreme events can cause both closed and penetrating TBI in the same person.

Certain groups are at higher risk of TBI:

• Men are more likely to get a TBI than women. They are also more likely to have serious TBI.
• Adults aged 65 and older are at the greatest risk for being hospitalized and dying from a TBI

The symptoms of TBI depend on the type of injury and how serious the brain damage is.

The symptoms of mild TBI can include:

• A brief loss of consciousness in some cases. However, many people with mild TBI remain conscious after the injury.
• Headache
• Confusion
• Lightheadedness
• Dizziness
• Blurred vision or tired eyes
• Ringing in the ears
• Bad taste in the mouth
• Fatigue or lethargy
• A change in sleep patterns
• Behavioral or mood changes
• Trouble with memory, concentration, attention, or thinking

If you have a moderate or severe TBI, you may have those same symptoms. You may also have other symptoms such as:

• A headache that gets worse or does not go away
• Repeated vomiting or nausea
• Convulsions or seizures
• Not being able to wake up from sleep
• Larger than normal pupil (dark center) of one or both eyes. This is called dilation of the pupil.
• Slurred speech
• Weakness or numbness in the arms and legs
• Loss of coordination
• Increased confusion, restlessness, or agitation

If you have a head injury or other trauma that may have caused a TBI, you need to get medical care as soon as possible. To make a diagnosis, your health care provider:

• Will ask about your symptoms and the details of your injury
• Will do a neurologic exam
• May do imaging tests, such as a CT scan or MRI
• May use a tool such as the Glasgow coma scale to determine how severe the TBI is. This scale measures your ability to open your eyes, speak, and move.
• May do neuropsychological tests to check how your brain is functioning

The treatments for TBI depend on many factors, including the size, severity, and location of the brain injury.

For mild TBI, the main treatment is rest. If you have a headache, you can try taking over-the-counter pain relievers. It is important to follow your health care provider's instructions for complete rest and a gradual return to your normal activities. If you start doing too much too soon, it may take longer to recover. Contact your provider if your symptoms are not getting better or if you have new symptoms.

For moderate to severe TBI, the first thing health care providers will do is stabilize you to prevent further injury. They will manage your blood pressure, check the pressure inside your skull, and make sure that there is enough blood and oxygen getting to your brain.

Once you are stable, the treatments may include:

• Surgery to reduce additional damage to your brain, for example to
  • Remove hematomas (clotted blood)
  • Get rid of damaged or dead brain tissue
  • Repair skull fractures
  • Relieve pressure in the skull
• Medicines to treat the symptoms of TBI and to lower some of the risks associated with it, such as
  • Anti-anxiety medication to lessen feelings of nervousness and fear
  • Anticoagulants to prevent blood clots
  • Anticonvulsants to prevent seizures
  • Antidepressants to treat symptoms of depression and mood instability
  • Muscle relaxants to reduce muscle spasms
  • Stimulants to increase alertness and attention
• Rehabilitation therapies, which can include therapies for physical, emotional, and cognitive difficulties:
  • Physical therapy, to build physical strength, coordination, and flexibility
  • Occupational therapy, to help you learn or relearn how to perform daily tasks, such as getting dressed, cooking, and bathing
  • Speech therapy, to help you to with speech and other communication skills and treat swallowing disorders
  • Psychological counseling, to help you learn coping skills, work on relationships, and improve your emotional well-being
  • Vocational counseling, which focuses on your ability to return to work and deal with workplace challenges
  • Cognitive therapy, to improve your memory, attention, perception, learning, planning, and judgment

Some people with TBI may have permanent disabilities. A TBI can also put you at risk for other health problems such as anxiety, depression, and post-traumatic stress disorder. Treating these problems can improve your quality of life.

There are steps you can take to prevent head injuries and TBIs:

• Always wear your seatbelt and use car seats and booster seats for children
• Never drive under the influence of drugs or alcohol
• Wear a properly fitting helmet when riding a bicycle, skateboarding, and playing sports like hockey and football
• Prevent falls by
  • Making your house safer. For example, you can install railings on the stairs and grab bars in the tub, get rid of tripping hazards, and use window guards and stair safety gates for young children.
  • Improving your balance and strength with regular physical activity

The uterus, or womb, is the place where a fetus grows during pregnancy. Uterine diseases are conditions that affect the uterus. These diseases can be benign (not cancer) or malignant (cancerous). They may affect your menstrual periods, your ability to get pregnant, or the health of your reproductive organs.

Some types of uterine diseases include:

• Adenomyosis. Tissue that usually lines the uterus grows on the outside walls.
• Cervicitis. Swelling or inflamed tissue of the cervix. The cervix is the lower part of the uterus.
• Endometrial hyperplasia. An overgrowth of normal cells inside the uterus.
• Endometriosis. Tissue like the lining of the uterus grows in other places in your body.
• Uterine prolapse. The uterus drops in to the vagina due to weakened pelvic muscles. This can happen after a few vaginal births, menopause, or because of obesity.

Various factors can cause uterine diseases. These can include hormonal imbalances, thyroid problems, fibroids, polyps, cancer, infection, or pregnancy.

Your symptoms will depend on the type of uterine condition you have. The first sign of a problem with the uterus may be abnormal bleeding. Bleeding could occur between periods, be very heavy, or last much longer than usual. Other symptoms may include bleeding after sex or pelvic pain.

To find out the cause of your symptoms, your health care provider may:

• Ask about your symptoms and medical history
• Do a pelvic exam
• Order blood tests or imaging tests
• Do a biopsy

Treatment depends on the cause. It may include pain medicine, hormone therapy, or surgery. Your provider will work with you to choose the best treatment.

Menstruation, or period, is a woman's monthly bleeding. Abnormal vaginal bleeding is different from normal menstrual periods. It could be bleeding that is between periods, is very heavy, or lasts much longer than usual. It also includes bleeding that happens before puberty or after menopause. Causes can include:

• Uterine fibroids or polyps
• Hormone problems
• Hormone pills, such as birth control pills and hormone replacement therapy (menopausal hormone therapy)
• Cancer of the cervix, ovaries, uterus or vagina
• Thyroid problems

Bleeding during pregnancy can have several different causes. It is not always serious, but to be safe you should contact your health care provider right away.

Pelvic exams, blood tests, imaging tests, and other procedures can help your health care provider diagnose the problem. Treatment depends on the cause. Treatments may include medicines, hormones, and surgery.