rh

There are four major blood types: A, B, O, and AB. The types are based on substances found on your blood cells. Your blood type also has a positive or negative sign. This is called Rh factor, which is a protein. If your blood cells have this protein, you are Rh-positive. If you don't, you are Rh-negative.

Rh factor is inherited (passed down through families). Most people are Rh-positive, meaning they have the Rh factor. Rh-negative people don't have it. Being Rh-negative doesn't affect your health, but it can affect the health of your fetus if you are pregnant.

If you are pregnant and are Rh-negative and your fetus is Rh-positive, it's called Rh incompatibility. Blood from your fetus can cross into your bloodstream, especially during childbirth. If you're Rh-negative and your baby is Rh-positive, your body will react to the fetus's blood as a foreign substance. It will create antibodies (proteins) that can damage their red blood cells.

These antibodies usually don't cause problems during your first pregnancy. But Rh incompatibility may cause problems in later pregnancies if the fetus is Rh-positive. This is because the antibodies stay in your body once they have formed. During your next pregnancy, the antibodies can cross the placenta (the organ that grows in the uterus to provide oxygen and nutrients to the fetus) and attack the red blood cells of the fetus. Rh incompatibility can cause Rh disease, a serious condition that can cause a severe type of anemia.

Your health care provider will order blood tests during your first trimester of pregnancy. This is often done at your first prenatal visit. These tests can check if you have Rh factor and if your body has made antibodies.

• During your pregnancy, injections of a medicine called Rh immune globulin can keep your body from making Rh antibodies. It helps prevent the problems of Rh incompatibility.
• After delivery, if your baby is born Rh-positive, you'll need another injection of the Rh immune globulin. But if you're Rh-negative and your baby is born Rh-negative, you don't need any other treatment.
• If treatment is needed for the baby, it may include phototherapy (light therapy) if treatment is needed for jaundice, supplements to help the body make red blood cells, or in severe cases a blood transfusion.

Early prenatal care and treatment help prevent issues with Rh incompatibility.

Your blood is made up of liquid and solids. The liquid part, called plasma, is made of water, salts, and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells, and platelets.

Red blood cells (RBC) deliver oxygen from your lungs to your tissues and organs. White blood cells (WBC) fight infection and are part of your immune system. Platelets help blood to clot when you have a cut or wound. Bone marrow, the spongy material inside your bones, makes new blood cells. Blood cells constantly die and your body makes new ones. Red blood cells live about 120 days, and platelets live about 6 days. Some white blood cells live less than a day, but others live much longer.

There are four blood types: A, B, AB, or O. Also, blood is either Rh-positive or Rh-negative. So if you have type A blood, it's either A positive or A negative. Which type you are is important if you need a blood transfusion. And your Rh factor could be important if you become pregnant - an incompatibility between your type and the baby's could create problems.

Blood tests such as blood count tests help doctors check for certain diseases and conditions. They also help check the function of your organs and show how well treatments are working. Problems with your blood may include bleeding disorders, excessive clotting and platelet disorders. If you lose too much blood, you may need a transfusion.

NIH: National Heart, Lung, and Blood Institute

Cerebral palsy (CP) is a group of neurologic disorders that cause problems with movement, balance, and posture. The first part of the name, cerebral, means having to do with the brain. The second part, palsy, means weakness or problems with using the muscles.

CP can range from mild to severe. The brain damage and the disabilities it causes are permanent. But treatments can improve the lives of people who have the condition. For example, treatments can help to improve their motor skills and ability to communicate.

There are different types of CP:

• Spastic cerebral palsy, which is the most common type. It causes increased muscle tone, stiff muscles, and awkward movements. Sometimes it only affects one part of the body. In other cases, it can affect both arms and legs, the trunk, and the face.
• Dyskinetic cerebral palsy, which causes problems controlling the movement of the hands, arms, feet, and legs. This can make it hard to sit and walk.
• Ataxic cerebral palsy, which causes problems with balance and coordination.
• Mixed cerebral palsy, which means that you have symptoms of more than one type.

CP is caused by abnormal development or damage to the developing brain. When this development or damage happens before birth, it is called congenital CP. Most CP is congenital, and its causes may include:

• Gene changes (variants)
• Brain malformations
• Infections or fevers in the pregnant parent
• An injury to the developing baby

CP can also happen during or after birth. CP that happens more than 28 days after birth is called acquired CP. Its causes can include:

• Brain damage in the first few months or years of life
• Infections, such as meningitis or encephalitis
• Problems with blood flow to the brain, for example from a stroke or abnormal blood vessels
• Head injuries, for example from a car accident, a fall, or child abuse

In some cases, the cause of congenital or acquired CP is unknown.

Certain medical conditions or events that can happen during pregnancy and delivery may increase a baby's risk of congenital cerebral palsy. These may include:

• Being born too small
• Being born too early
• Being born a twin or other multiple birth
• Being conceived by in vitro fertilization (IVF) or other assisted reproductive technology (ART)
• Infections
• Health problems in the pregnant parent, such as thyroid problems and seizures
• Severe newborn jaundice
• Having complications during birth
• Rh incompatibility
• Exposure to toxic chemicals during pregnancy

There are many different types and levels of disability with CP. So the signs can be different in each child. These signs usually appear in the early months of life. They may include:

• Developmental delays. Your child may be slow to reach developmental milestones such as learning to roll over, sit, crawl, or walk.
• Abnormal muscle tone. Your child may seem floppy, or they may be stiff or rigid.
• An unusual posture or favoring one side of the body when reaching, crawling, or moving.
• Stiff or tight muscles and exaggerated reflexes (spasticity).
• Shaking (tremor) of arms, legs, hands, or feet.
• Sudden, uncontrolled movements.

It's important to know that children without CP can also have these signs. Contact your child's health care provider if your child has any of these signs, so you can get a correct diagnosis.

Diagnosing CP involves several steps:

• Developmental monitoring (or surveillance) means tracking a child's growth and development over time. If there are any concerns about your child's development, they should have a developmental screening test as soon as possible.
• Developmental screening involves giving your child a short test to check for motor, movement, or other developmental delays. If the screenings are not normal, the provider will recommend more evaluations.
• Developmental and medical evaluations are done to diagnose which disorder your child has. To make the diagnosis, your provider:
  • Will check your child's motor skills, muscle tone, reflexes, and posture
  • Will ask about their medical history
  • May order lab tests, genetic tests, and/or imaging tests

There is no cure for CP, but treatment can improve the lives of those who have it. It is important to begin a treatment program as early as possible.

A team of health professionals will work with you and your child to develop a treatment plan. Common treatments include:

• Medicines
• Surgery
• Assistive devices such as braces and walkers
• Physical, occupational, recreational, and speech therapy

You cannot prevent the genetic problems that can cause CP. But it may be possible to manage or avoid some of the risk factors for CP. For example:

• If you are pregnant, make sure that you are vaccinated against infections that could cause CP in your developing baby.
• Get regular prenatal care, which can reduce the risk of preterm birth or having a low birthweight baby. It can also help you manage any health conditions that could raise the risk of CP.
• Use car seats for your baby to prevent head injuries that could cause CP.

A health problem in pregnancy is any disease or condition that could affect your health or the health of your fetus. Some health problems may make it more likely that you will have a high-risk pregnancy. A high-risk pregnancy is one in which you, your fetus, or both are at higher risk for health problems than in a typical pregnancy.

But just because you have health problems, it doesn't mean that you, or your fetus, will have a problem during the pregnancy. Taking care of yourself and getting early and regular prenatal care from a health care provider may help you reduce pregnancy risks from health problems.

Every pregnancy has some risk of problems, but your lifestyle, as well as factors like certain conditions and health issues, can raise that risk, such as:

• A health condition you had before you got pregnant
• A health condition you develop during pregnancy
• A pregnancy with more than one baby
• A health problem that happened during a previous pregnancy and could happen again
• Substance use during pregnancy
• Being over age 35

Any of these can affect your health, the health of your fetus, or both.

Every pregnancy is different. If you have specific risks in one pregnancy, it doesn't mean that you will have them in another. But, if you have a chronic condition, you should talk to your provider about how to minimize your risk before you get pregnant. Once you are pregnant, you may need a health care team to monitor your pregnancy. Some common conditions that can complicate a pregnancy include:

• High blood pressure
• Polycystic ovary syndrome (PCOS)
• Kidney problems
• Autoimmune disorders
• Thyroid disease
• Obesity
• HIV
• Cancer
• Infections

Other conditions that may make pregnancy risky can develop during pregnancy - for example, gestational diabetes and Rh incompatibility.

You may be able to lower your risk of certain health problems by making healthy lifestyle changes before you get pregnant. These can include reaching a healthy weight, not smoking, and managing any health conditions.

However, health problems during pregnancy are not always preventable. Some chronic conditions can be treated and controlled, while others aren't treatable and carry a higher risk than usual, even if the health problem is well-managed.

Share your symptoms with your provider for early detection and treatment of health problems. Sometimes, it's hard to know what's normal. Some symptoms, like nausea, back pain, and fatigue, are common during pregnancy, while other symptoms, like vaginal bleeding or a severe or long-lasting headache, can be signs of a problem. Call your provider to let them know if something is bothering or worrying you.

A miscarriage is an unexpected loss of pregnancy before the 20th week. Most miscarriages happen very early in the pregnancy, often before a woman even knows she is pregnant.

A miscarriage can happen in any pregnancy. Most miscarriages occur because the fetus doesn't develop properly. This is often linked to a genetic problem with the fetus, such as an extra or missing chromosome.

In many cases, the cause of a miscarriage is unknown. Some possible factors that may increase the chance of a miscarriage can include:

• Problems with the uterus or cervix
• Chronic diseases, including polycystic ovary syndrome
• Genetic problems with the fetus
• Pregnancy after 35 years of age
• Smoking, drug or alcohol use
• Certain chronic (long-term) health conditions, such as uncontrolled diabetes
• Severe malnutrition

The signs of a miscarriage may be different for everyone and can vary based on how far along you are in your pregnancy.

Signs of a miscarriage can include:

• Vaginal spotting or bleeding with or without pain. Some women may have some spotting in early pregnancy and don't miscarry. To be sure, contact your provider right away if you have any bleeding.
• Dark-colored vaginal discharge.
• A gush of fluid or tissue from your vagina.
• Cramping or pain in your abdomen (belly) or lower back.

Sometimes, it's hard to know what's normal during pregnancy. If something seems unusual or is worrying you, talk to your provider.

To check if you have had a miscarriage, your provider may do the following:

• A pelvic exam to check your cervix.
• Blood tests to check things such as the amount of blood loss and confirm pregnancy.
• An ultrasound to check the fetus.

Treatment after a miscarriage often depends on when it occurs during the pregnancy. If you miscarry early in your pregnancy, you may not need any treatment. If you are 12 or more weeks pregnant, you may need a shot to prevent problems with the Rh factor in future pregnancies.

In some cases, tissue is left in the uterus. If you don't have any signs of infection, your provider may recommend waiting for the tissue to pass naturally. If you need treatment to remove the tissue, it can include:

• Medicines
• A procedure called dilatation and curettage (D&C) or vacuum aspiration

No matter when it occurs, losing a pregnancy can be difficult. Counseling may help you cope with your grief. Later, if you decide to try to get pregnant again, talk with your provider to understand any risks. Many women who have a miscarriage go on to have healthy pregnancies later.

Miscarriage can affect anyone and often can't be prevented. Focus on taking good care of yourself and start prenatal care visits early in your pregnancy.

NIH: National Institute of Child Health and Human Development

Prenatal testing provides information about the health of your fetus before the baby is born. Some routine tests during pregnancy also check your health. The prenatal test may use a sample of your blood, urine or fluid from your vagina, cervix, or rectum.

Since some health conditions can be treated before your baby is born, it's important to find them early. But even if they cannot be treated, it can still be helpful to know about the problem early on. This gives you time to learn about the condition and prepare for any challenges you may face after the baby is born.

At your first prenatal visit, your health care provider will test for various conditions, including problems with your blood, signs of infections, and whether you are immune to rubella (German measles) and chickenpox.

Throughout your pregnancy, your provider may recommend additional tests as well. Some tests are suggested for all women, such as screenings for gestational diabetes, Down syndrome, and HIV.

Your provider might offer other tests based on your:

• Age
• Personal or family medical history
• Ethnic background
• Results of routine tests

There are two types of tests:

• Screening tests check if you or your fetus may have certain health issues. They look at risk but do not diagnose problems. If your screening test result is abnormal, it does not mean that there is a problem. It means that more information is needed. Your provider can explain what the test results mean and possible next steps. You may need diagnostic testing.
• Diagnostic tests help determine whether you or your fetus have a certain health problem.

It is your choice whether to get prenatal tests. You and your provider can talk about the risks and benefits of the tests, as well as the type of information they can give you. Then you can decide which ones are right for you.

National Women's Health Information Center

Your blood is living tissue made up of liquid and solids. The liquid part, called plasma, is made of water, salts and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells and platelets.

Blood disorders affect one or more parts of the blood and prevent your blood from doing its job. They can be acute or chronic. Many blood disorders are inherited. Other causes include other diseases, side effects of medicines, and a lack of certain nutrients in your diet.

Types of blood disorders include:

• Platelet disorders, excessive clotting, and bleeding problems, which affect how your blood clots
• Anemia, which happens when your blood does not carry enough oxygen to the rest of your body
• Cancers of the blood, such as leukemia and myeloma
• Eosinophilic disorders, which are problems with one type of white blood cell.

It can be scary when your baby is sick, especially when it is not an everyday problem like a cold or a fever. You may not know whether the problem is serious or how to treat it. If you have concerns about your baby's health, call your health care provider right away.

Learning information about your baby's condition can help ease your worry. Do not be afraid to ask questions about your baby's care. By working together with your health care provider, you make sure that your baby gets the best care possible.