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Many Americans drink alcohol at least occasionally. The Dietary Guidelines for Americans say that adults of legal drinking age should either not drink or drink in moderation. Drinking less is better for your health than drinking more. Also, there are some people who should not drink at all.

If you are going to drink, it's important to know how alcohol affects you and how much is too much.

Alcohol is a central nervous system depressant. This means that it is a drug that slows down brain activity. It can change your mood, behavior, and self-control. It can cause problems with memory and thinking clearly. Alcohol can also affect your coordination and physical control.

Alcohol also has effects on the other organs in your body. For example, it can raise your blood pressure and heart rate. If you drink too much at once, it could make you throw up.

Alcohol's effects vary from person to person, depending on a variety of factors, including:

• How much you drink
• How often you drink
• Your age
• Your sex
• Your genetics
• Your overall health
• Whether or not you have a family history of alcohol problems

• For most women, moderate drinking is no more than 1 standard drink a day
• For most men, moderate drinking is no more than 2 standard drinks a day

Even though moderate drinking may be safe for many people, there are still risks. Moderate drinking can raise the risk of death from certain cancers and heart diseases.

In the United States, a standard drink is one that contains about 14 grams of pure alcohol, which is found in:

• 12 ounces of regular beer (5% alcohol content)
• 5 ounces of wine (12% alcohol content)
• 1.5 ounces or a "shot" of distilled spirits or liquor (40% alcohol content)

Some people should not drink alcohol at all, including those who:

• Are in recovery from an alcohol use disorder (AUD)
• Are are unable to control the amount they drink
• Are under age 21
• Are pregnant or trying to become pregnant
• Are taking medicines that can interact with alcohol
• Have medical conditions that get can worse if you drink alcohol
• Are planning on driving
• Will be operating machinery or doing activities that require skill, coordination, and alertness

If you have questions about whether it is safe for you to drink, talk with your health care provider.

Excessive drinking includes binge drinking and heavy alcohol use:

• Binge drinking is drinking so much at once that your blood alcohol concentration (BAC) level is 0.08% or more:
  • For men, this usually happens after having 5 or more drinks within a few hours.
  • For women, it is usually after about 4 or more drinks within a few hours.
• Heavy alcohol use means:
  • For men, having more than 5 drinks on any day or more than 15 drinks per week.
  • For women, having more than 4 drinks on any day or more than 8 drinks per week.

Binge drinking raises your risk of injuries, car crashes, and alcohol overdose. It also puts you at risk of becoming violent or being the victim of violence.

Heavy alcohol use over a long period of time may cause health problems such as:

• Alcohol use disorder (AUD)
• Liver diseases, including cirrhosis and fatty liver disease
• Heart diseases
• Increased risk of certain cancers
• Increased risk of injuries

Heavy alcohol use can also cause problems at home, at work, and with friends. But treatment can help.

NIH: National Institute on Alcohol Abuse and Alcoholism

COVID-19 (coronavirus disease 2019) is a disease caused by a virus called SARS-CoV-2. There are two types of tests for this virus:

• A viral test tells you if you have a current infection. Viral tests can either be rapid tests or laboratory tests:
  • Rapid tests can be done in minutes. They are often antigen tests, which look for specific proteins from the virus. Some rapid tests are self-tests which you can do at home.
  • Laboratory tests can take days to complete and include PCR tests.
• An antibody (serology) test might tell you if you had a past infection.

If you need a COVID-19 test, you can:

• Buy a self-test online or at a store. Make sure that the test you buy has been authorized by the U.S. Food and Drug Administration (FDA).
• Check your state or local health department's website for information on testing in your area.
• Contact your health care provider.

Even if your COVID-19 viral test is negative (the test did not detect the virus), you should still take steps to protect yourself and others.

Centers for Disease Control and Prevention

Before any drug can be sold in the United States, it must be approved by the U.S. Food and Drug Administration (FDA). This is true whether it's a prescription or an over-the-counter drug. The FDA evaluates both the effectiveness and safety of a drug by looking at:

• How animal testing and human clinical trials affect the condition the drug is treating
• If any side effects occur
• How it's manufactured
• What the labeling says

The FDA also monitors a drug's safety after approval. Health care providers and patients can report drug side effects through the FDA's MedWatch website.

For you, drug safety means buying online only from licensed pharmacies located in the United States. It also means knowing how to take your medicines correctly.

Hemophilia is a rare bleeding disorder in which the blood does not clot properly. This can lead to problems with bleeding too much after an injury or surgery. You can also have sudden bleeding inside your body, such as in your joints, muscles, and organs.

Your blood contains many proteins called clotting factors that can help form clots to stop bleeding. People with hemophilia have low levels of one of these factors, usually either factor VIII (8) or factor IX (9). How severe the hemophilia is depends on the amount of factor in the blood. The lower the amount of the factor, the more likely it is that bleeding could happen and might lead to serious health problems.

There are several different types of hemophilia. The most common are:

• Hemophilia A (classic hemophilia), which is caused by a lack or decrease of clotting factor VIII (8)
• Hemophilia B (Christmas disease), which is caused by a lack or decrease of clotting factor IX (9)

Most types of hemophilia are inherited. They are caused by change in one of the genes (also called a mutation) that provides instructions for making the clotting factor proteins. The change may mean that the clotting proteins don't work properly or that they are missing altogether.

These genes are on the X chromosome. You may have one or two X chromosomes:

• People who are born male have one X chromosome (from the mother) and one Y chromosome (from the father). They can get hemophilia if their one X chromosome has the gene change.
• People who are born female have two X chromosomes, one from the father and one from the mother. They usually only get hemophilia if:
  • Both X chromosomes have the gene change OR
  • One X chromosome has the gene change and the other X chromosome is missing or inactive.

  People who are born female who have the gene change on one X chromosome are a "carrier" of hemophilia. Sometimes they may have some symptoms of hemophilia. They can pass the gene change on to their children.

Hemophilia that is not inherited is called acquired hemophilia. It is rare. It happens when your body makes specialized proteins called autoantibodies that attack and disable a clotting factor. This can happen because of pregnancy, immune system disorders, cancer, or allergic reactions to certain medicines. Sometimes the cause is unknown.

Hemophilia is much more common in people who were born male since they can get it with a change to the gene on one X chromosome. People who have a family history of hemophilia are also at higher risk.

The signs and symptoms of hemophilia are:

• Bleeding into the joints. This can cause swelling and pain or tightness in the joints. It often affects the knees, elbows, and ankles.
• Bleeding into the skin (which is bruising).
• Bleeding into the muscle and soft tissue, which can cause a build-up of blood in the area (called a hematoma).
• Bleeding of the mouth and gums, including bleeding that is hard to stop after you lose a tooth.
• Bleeding after circumcision.
• Bleeding after having shots, such as vaccinations.
• Bleeding in the head of an infant after a difficult delivery.
• Blood in the urine or stool.
• Frequent and hard-to-stop nosebleeds.

In some cases, severe hemophilia may cause bleeding in the brain. This may cause brain damage and can be life-threatening.

To find out if you have hemophilia, your health care provider will:

• Ask about your medical history, including your symptoms and other health conditions you may have.
• Ask about your family history, to find out if you have relatives who have or had hemophilia.
• Do a physical exam to look for signs of hemophilia, such as bruising.
• Do certain blood tests to show if your blood is clotting properly. If it does not, then you will have clotting factor tests to diagnose the cause of the bleeding disorder. These blood tests would show the type of hemophilia and the severity.

There is genetic testing for the factor VIII (8) and factor IX (9) genes. This testing may be used in people who have a family history of hemophilia to:

• Identify people who are carriers before they make decisions about pregnancy
• Test a fetus for hemophilia during pregnancy
• Test a newborn for hemophilia

The best way to treat hemophilia is to replace the missing clotting factor so that your blood can clot properly. This is usually done by injecting replacement clotting factor into a vein. The replacement clotting factor may be made from donated human blood. Or it may be made in a lab; this kind is called a recombinant clotting factor.

Replacement clotting factor can help treat a bleeding episode. In more severe cases of hemophilia, you might get the factor on a regular basis to prevent bleeding. You can learn how to inject the factor so that you can do it yourself at home.

There are other medicines to treat hemophilia. They may work by releasing factor VIII (8) from where it is stored in the body tissues, replacing the function of factor VIII (8), or preventing clots from breaking down.

If bleeding has damaged your joints, physical therapy may help them function better.

Good quality medical care from healthcare professionals who know a lot about the disorder can help prevent some serious problems. Often the best choice for care is to visit a hemophilia treatment center (HTC).

Centers for Disease Control and Prevention

Intimate partner violence (IPV) is abuse that happens in a romantic relationship. The intimate partner could be a current or former spouse or dating partner. IPV is also known as domestic violence.

IPV may include different types of abuse, such as:

• Physical violence, when a person hurts or tries to hurt a partner by hitting, kicking, or using another type of physical force.
• Sexual violence which involves forcing or attempting to force a partner to take part in sexual activity when the partner does not or cannot consent. The sexual activity could include things like sex acts, sexual touching, or non-physical sexual events (e.g., sexting).
• Emotional abuse, which includes threats, name-calling, put-downs, and humiliation. It can also involve controlling behavior, such as telling a partner how to act or dress and not letting them see family or friends.
• Economic abuse, also called financial abuse, which involves controlling access to money.
• Stalking, which is repeated, unwanted contact that causes fear or concern for the safety of the partner. This can include watching or following the partner. The stalker may send repeated, unwanted phone calls or texts.

It is hard to know exactly how common IPV is because it is often not reported.

But we do know that anyone can be affected by it. IPV can happen to anyone. It affects people with all levels of income and education.

If you think that a loved one might be experiencing IPV, watch for these signs:

Does your friend or loved one:

• Have unexplained cuts or bruises?
• Avoid friends, family, and favorite activities?
• Make excuses for their partner's behavior?
• Look uncomfortable or fearful around their partner?

Does your friend or loved one's partner:

• Yell at or make fun of them?
• Try to control them by making all the decisions?
• Check up on them at work or school?
• Force them to do sexual things they don't want to do?
• Threaten to hurt themself if the partner wants to break up?

Your safety is the most important concern. If you are in immediate danger, call 911.

If you are not in immediate danger, you can:

• Get medical care if you have been injured or sexually assaulted.
• Call a helpline for free, anonymous help. You can contact the National Domestic Violence Hotline at 800-799-SAFE (7233) or 800-787-3224 (TTY). You can also chat with them through their website or through text by texting START to 88788.
• Find out where to get help in your community. Contact local organizations that can help you.
• Make a safety plan to leave. Intimate partner violence usually does not get better. Think about a safe place for you to go and all of the things that you will need when you leave.
• Save the evidence. Keep evidence of abuse, such as pictures of your injuries or threatening emails or texts. Make sure that it is in a safe place the abuser cannot access.
• Talk to someone you trust, such as a family member, a friend, a co-worker, or a spiritual leader.
• Consider getting a restraining order to protect yourself.

Let your loved one know that being treated this way isn't healthy and that they are not to blame. You should:

• Call 911 if there is immediate danger.
• Watch for the signs of abuse. Learn about the signs and keep track of the ones that you see.
• Find out about local resources. Get the addresses and phone numbers of some local resources in your community. Then you'll be able to share the information if the person is ready for it.
• Set up a time to talk. Make sure you can have your conversation in a safe, private place. Your loved one's partner may have access to his or her cell phone or computer, so be careful about sharing information over text or email.
• Be specific about why you are worried. Describe the behaviors that concern you. Be as specific as possible when explaining why you are worried.
• Plan for safety. If your loved one is ready to leave an abusive partner, help make a plan for getting out of the relationship as safely as possible. An intimate partner violence counselor can help with making a safety plan.
• Be patient and do not judge. You should talk about your concerns with your loved one, but you need to understand that they may not be ready to talk about it. Let them know that you're available to talk at any time, and that you will listen without judging them.

Suicide is the taking of one's own life. It is a death that happens when someone harms themselves because they want to end their life. A suicide attempt is when someone harms themselves to try to end their life, but they do not die.

Suicide is a major public health problem and a leading cause of death in the United States. Both suicide and suicide attempts can have lasting harmful effects:

• People who survive a suicide attempt may have serious injuries that can affect their long-term health. They may also have depression or other mental health concerns.
• When people die by suicide, it affects their family, friends, and community. They may feel grief, shock, anger, and guilt. Some may develop post-traumatic stress disorder (PTSD), depression, or anxiety. They may also be at risk for suicidal thoughts.

Suicide does not discriminate. It can touch anyone, anywhere, at any time. But there are certain factors that can contribute to the risk of suicide, including:

• Having attempted suicide before
• Depression and other mental health disorders
• Alcohol or drug use disorder
• Family history of a mental health disorder
• Family history of an alcohol or drug use disorder
• Family history of suicide
• Family violence, including intimate partner violence, child abuse, or sexual abuse
• Having guns in the home
• Being in or having recently gotten out of prison or jail
• Being exposed to others' suicidal behavior, such as a family member, peer, or celebrity
• Medical illness, including chronic pain
• Stressful life event, such as a job loss, financial problems, loss of a loved one, a breakup of a relationship, etc.
• Being between the ages of 15 and 24 years or over age 60

The warning signs for suicide include:

• Talking about wanting to die or wanting to kill oneself
• Making a plan or looking for a way to kill oneself, such as searching online
• Buying a gun or stockpiling pills
• Feeling empty, hopeless, trapped, or like there's no reason to live
• Being in unbearable pain
• Talking about being a burden to others
• Using more alcohol or drugs
• Acting anxious or agitated; behaving recklessly
• Sleeping too little or too much
• Withdrawing from family or friends or feeling isolated
• Showing rage or talking about seeking revenge
• Displaying extreme mood swings
• Saying good-bye to loved ones, putting affairs in order

Some people may tell others about their suicidal thoughts. But others may try to hide them. This can make some of the signs harder to spot.

If you or someone you know has the warning signs for suicide, get help right away, especially if there is a change in behavior. If it is an emergency, dial 911. Otherwise there are five steps that you can take:

• Ask the person if they're thinking about killing themselves.
• Keep them safe. Find out whether they have a plan for suicide and keep them away from things that they can use to kill themselves.
• Be there with them. Listen carefully and find out what they are thinking and feeling.
• Help them connect to resources that can help them, such as through:
  • Calling or texting the 988 Suicide & Crisis Lifeline at 988.
  • Chatting through Lifeline Chat.
  • For veterans, reaching the Veterans Crisis Line by:
    • Calling 988 and then pressing 1.
    • Texting to 838255.
    • Chatting with them.
• Stay connected. Staying in touch after a crisis can make a difference.

NIH: National Institute of Mental Health

Military service members and veterans have made sacrifices to our country, and they may face lots of different health issues. Some of the most common health problems they may have include chronic pain, sleep disorders, and mental health disorders.

But they may also face some different health risks than civilians. Serving to protect our country is a special job, and along with it comes some special risks and job hazards. These include different types of injuries and health problems from exposures.

During their service, members are at risk for various injuries. These injuries can happen during training or while in combat. Sometimes the injuries are life-threatening or serious enough to cause disability. Others may not be as serious, but they may be painful and can affect daily life.

Some of the specific types of injuries that service members may face include:

• Sprains and strains, especially in the ankles and knees. These injuries are often caused by exercise and running.
• Back and shoulder injuries, often from lifting and carrying.
• Tinnitus and hearing loss, typically from exposure to noise.
• Head injuries and traumatic brain injuries (TBIs).
• Shrapnel and gunshot wounds.
• Lost limbs.

There may also be a risk of health problems from exposure to environmental hazards, such as contaminated water, chemicals, infections, and burn pits. Sometimes the health problems caused by exposures don't develop until years later.

Some service members experience military sexual trauma (MST). This includes sexual assault and sexual harassment.

Being in combat and being separated from your family can be stressful. So can readjusting to civilian life after the military. All of this stress can put service members and veterans at risk for mental health problems, including:

• Depression
• Post-traumatic stress disorder (PTSD)
• Anxiety
• Alcohol and drug use disorders

There is also a risk of suicide. Veterans who are in crisis can get help from the Veteran's Crisis line by:

• Calling 988 and then pressing 1
• Texting to 838255
• Chatting with them online

There are health care services especially for service members and veterans through:

• TRICARE, which is the Department of Defense's health care program. It has insurance plans and other services for uniformed service members, retirees, and their families around the world.
• The Veterans Health Administration, which is part of the Department of Veterans Affairs (VA). It provides medical and social support services to eligible veterans.
• The VA 's expanded health care and benefits for veterans exposed to burn pits, Agent Orange, and other toxic substances.

To better understand and treat the health needs of veterans in the future, the VA created the Million Veteran Program (MVP). This research program is looking at how genes, lifestyle, military experiences, and exposures affect health and wellness in veterans.